Vancomycin-induced nephrotoxicity with unusual high serum trough level in a critically ill young patient
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چکیده
منابع مشابه
9 Vancomycin - Induced Nephrotoxicity
Nephrotoxicity associated with vancomycin administration has been a topic of debate for over five decades (Tables 1 & 2). Vancomycin is a glycopeptide antibiotic excreted by the kidney and has been used extensively, especially for methicillin-resistant staphylococcus aureus (MRSA) and for many strains of pathogenic staphylococcus epidermis. The nephrotoxic potential of vancomycin is neither ful...
متن کاملIdentification of risk factors for nephrotoxicity in patients receiving extended-duration, high-trough vancomycin therapy.
BACKGROUND In the past, impurities in vancomycin formulations were thought to contribute to nephrotoxicity. In contrast, when current, purer formulations are dosed at conventional trough levels (i.e., 5-15 mg/L), the incidence of nephrotoxicity is relatively low. Recent guidelines have recommended targeting higher vancomycin trough levels in treatment of complicated methicillin-resistant Staphy...
متن کاملFree Perforation of Sigmoid Colon Secondary to Invasive Mucormycosis in a Critically Ill Patient
Mucormycosis is a clinical entity attributed to opportunistic fungal infection of order Mucorales. This includes several pathogenic subtypes. It commonly affects the rhinocerebral sites and the immunocompromized patients with devastating results. Visceral mucormycosis is a relatively rare complication. We report the first free sigmoid colon perforation secondary to invasive mucormycosis and dis...
متن کاملReply to "Vancomycin-induced nephrotoxicity".
S. J. van Hal, D. L. Paterson, T. P. Lodise Department of Microbiology & Infectious Diseases, Royal Prince Alfred Hospital, Sydney, Australia; Antibiotic Resistance & Mobile Elements Group, Microbiology and Infectious Diseases Unit, School of Medicine, University of Western Sydney, Sydney, Australia; University of Queensland Centre for Clinical Research (UQCCR), Herston, Australia; Albany Colle...
متن کاملNephrotoxicity of vancomycin in patients with normal serum creatinine.
Chronic renal disease is frequent in the general population. In the case of epidemia or pandemia of avian influenza A (H5N1), the two neuraminidase inhibitors, oseltamivir and zanamivir will therefore be used in patients with renal impairment. Although zanamivir does not necessitate any adjustment of its dosage in patients with renal failure, because it is not absorbed after oral inhalation, os...
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ژورنال
عنوان ژورنال: Archives of Pharmacy Practice
سال: 2016
ISSN: 2045-080X
DOI: 10.4103/2045-080x.186178